S-4 is by far the most versatile SARM ever created. Not only is it the first SARM approved for a stage 2 research study, it has become the most analyzed and investigated SARM so far. After the discovery of its anabolic potential, the primary purpose of S-4 aimed to develop an alternative treatment to age-related muscle wasting, osteoporosis, and similar symptoms of hypogonadism, or end-stage renal disease.
Aside from preserving lean body mass, S4 can also help improve it.
From a stage 1 study, S-4 has provided evidence of a 3.3 lbs increase in less than 90 days with no increases exercise or change in daily diet. An unintended side effect (or benefit if you will) is the decrease in body fat [Chen et al., 2005; Gao et al., 2005; Kearbey et al., 2007]. Decreases in body fat are dependent on the person’s genetics, but it will definitely have strong effects on the body’s ability to oxidize fatty tissue. S-4 was found to not only have a great affinity (potency in binding to androgen receptors), while also presenting greater anabolic effects than some traditional steroids [Kearbey et al., 2007].
Aside from its muscle building advantages, S4 won’t cause liver damage, can prevent gynecomastia (enlarged breasts in men) and can help boost your overall health.
Here are some of the other benefits of Andarine that are worth noting:
- Very minimal growth on secondary sexual organs such as the prostate.
- The LDL/ HDL ratio is not affected which makes it a low cardiovascular risk.
- 0% chance of aromatization, male breast lactation, or rise in any other female characteristic during the post cycle recovery. [Kearbey et al., 2007]
- Testosterone is not diminished in any capacity during the post cycle recovery.
- Very exclusive in tissue selection and growth which means it will not cause heart enlargement or damage to neighboring organs.
- SARMs do NOT require the utilization or devouring of liver enzymes to activate their anabolic effects. This eliminates any risk of hepatotoxicity or hepatitis.
- Although SARMs such as S-4 are not as powerful as comparable steroids such as Winstrol, they do not require the extensive post cycle therapy and can be cycled back to back throughout the year. Over the course of a year, obtaining the same results is very possible.
- SARMs is very female friendly and does not cause excessive masculine features such enlarged sexual characteristics.
- S-4 has overall presented larger increases in muscle mass than DHT.
FULL MUSCLE REGENERATION & LEAN BODY MASS
Once more, an early study done on S-4 provided proof of full muscle regeneration in volunteers with degenerative disorders without the use of exercise and the minimum dosage of 3mg/kg/day. Changes can be seen anywhere from 1-2 weeks. This was the very first study classified S-4 as CLINICALLY SIGNIFICANT by improving skeletal muscle strength, lean body mass, and a reduction in body fat [Chen et al., 2005; Gao et al., 2005; Kearbey et al., 2007]. Unfortunately, there are always some side effects that arise when using Because S-4 is a ligand by definition, the side effects will never be permanent even at supraphysiological dosages and can be easily avoided through proper dosing.
THE SIDE EFFECTS: WHAT YOU “SEE” IS WHAT YOU GET
Unfortunately, there are always some side effects that arise when using Because S-4 is a ligand by definition, the side effects will never be permanent even at supraphysiological dosages and can be easily avoided through proper dosing. Also, Andarine follows the law of diminishing returns meaning that over time, your body will develop a tolerance and the SARM will become less effective after a certain milligram percentage. For the average person it ranges from 50mg to 75mg. there are people that can go above this range for even more amazing results or need to stay below this range because they are unable to tolerate the chemical. About 99.5% of the population should fall within the 50mg to 75mg range.
The most popular negative effects of S-4 are visual issues such as the yellow tint and difficulty adjusting to night vision. These side effects are unique to S-4 and are sometimes overblown. If these side effects present themselves, simply stop taking S-4 for two days and stay at a 5 day on/ 2 day off cycle. THESE EFFECTS ARE NOT PERMANENT! Once a ligand (such as a SARM) leaves the system, it’s effects disappear completely.
Lastly, S-4 and most other SARMs have been known to cause depression in a small population of people. This has been discovered as more of a psychological issue than a physiological issue. researchers with mice suffering from any emotional disorders need to be cautious when using this chemical.
Benefits of Andarine have been reported with dosages ranging between 25mg and 50mg 3x per day.
Unfortunately, the higher the dosage, the higher the side effects. S4 is a rare form of SARM that has a greater risk of side effects than most other SARMs.
These effects are not permanent. S4 has been proven safe and effective for cycles up to 3 months.
Results may vary from person to person
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We make no ‘therapeutic claims’. Therapeutic goods are broadly defined by the TGA as products for use in humans in connection with:
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