LeGenD (LGD-4033) is a Selective Androgen Receptor Modulator or SARM for short
Ligandrol is often described as the “super osta” or the “king of sarms” due to it being highly selective like Ostarine but exerting its effects more forcefully, leading to greater muscle gains. LGD is a strong agonist for the AR in skeletal muscle and bone but very weak in comparison in the prostate.
At just 1mg per day for 3 weeks a clinical trial showed an average gain of 1.21kg in LBM which is nearly 1 pound of LBM per week which is absolutely insane considering the time frame and the fact that they were not even training. No fat loss was noted at all during this study. Unlike Ostarine, LGD-4033 does not seem to increase liver enzymes however like Ostarine it did negatively affect good cholesterol levels (HDL).
The biggest downside with LGD is that it caused moderate to strong HPTA suppression (natural testosterone suppression) for both total and free testosterone. Total testosterone decreased by just over 50% compared to placebo. But hormone levels did return to normal within 56 days after stopping with no PCT.
Ligand Pharmaceuticals has also completed acute safety studies on Ligandrol with no serious adverse events reported in dosages up to 22mg daily.
The usual dosage for performance enhancement is 2-10mg per day for 4-8 weeks. The average results from this are 7-10lbs of LBM, good increases in strength and little to no fat loss. Which makes it the perfect “muscle building SARM”.
Due to the HPTA suppression a PCT is needed post cycle for 4 weeks followed by an equal or greater amount of time off after the PCT period.
As an adult food supplement, take 1 capsule twice daily with meals. Do not exceed more than 2 capsules in a 24 hour period of time.
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