Radar1ne (RAD-140) is a Selective Androgen Receptor Modulator or SARM for short
Studies show that RAD-140 has a much higher binding affinity for the androgen receptor than testosterone and dihydrotestosterone. It also showed that it was highly selective in skeletal muscle and bone, with only a weak antagonistic effect in androgenic tissues. RAD-140 does also have an extremely weak interaction with progesterone and estrogen due to it not reacting with any other steroid hormone receptors to any appreciable degree.
RAD-140 did progress to animal studies but is yet to move to human trials. During this time researchers found that in rats RAD-140 matched anabolic effect with testosterone propionate mg for mg but was far less androgenic. It required a 60x higher dosage than the testosterone to cause the same prostate growth. When researchers did a study on monkeys, which is considered more clinically relevant to humans, their weight increased by 10% in 28 days and was almost exclusively LBM.
Side effects of RAD-140 are mostly unknown due the lack of human trials and was only first described in 2010 by Miller et al, developed by Radius Health. It is widely accepted that side effects are also dose dependent (higher the dosage, greater the risk of side effects).
RAD-140 is most commonly used at 5-20mg per day, with 10mg per day being the most common for 6-12 weeks. During this time people have reported large increases in strength as well as 10-15lbs of muscle from the first cycle.
As an adult food supplement, take 1 capsule twice daily with meals. Do not exceed more than 2 capsules in a 24 hour period of time.
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